Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung

A comprehensive understanding of airflow characteristics and particle transport in the human lung can be useful modelling to inform clinical diagnosis, treatment, management, including prescription medication risk assessment for rehabilitation. One difficulties treatment disorders lies patients’ variable physical caused by age, amongst other factors, such as different sizes. precise comparison between age groups with various flow rates is missing literature, this study aims analyse aerosol within age-specific lung. ANSYS Fluent solver large-eddy simulation (LES) model were employed numerical simulation. The was validated available literature computational results showed airway size-reduction significantly affected upper airways. This reports higher deposition at mouth-throat region larger diameter particles. overall efficiency (DE) increased size reduction rate. Lung aging effected pressure distribution a drop reported aged compared younger These findings could medical management through individualised drug-aerosol delivery processes patient-specific